极品美女娇喘呻吟-极品美女啪啪-极品美女翘臀爆乳高潮娇喘-极品美女无套内射-极品美女无套啪啪-极品美女中出

最近搜索:細胞培養 微生物學 分子生物 生物化學
首頁>>免疫學>>一抗>>磷脂酰肌醇結合網格蛋白組裝蛋白抗體
磷脂酰肌醇結合網格蛋白組裝蛋白抗體
  • 產品貨號:
    BN40323R
  • 中文名稱:
    磷脂酰肌醇結合網格蛋白組裝蛋白抗體
  • 英文名稱:
    Rabbit anti-PICALM Polyclonal antibody
  • 品牌:
    Biorigin
  • 貨號

    產品規格

    售價

    備注

  • BN40323R-100ul

    100ul

    ¥2360.00

    交叉反應:Mouse,Rat(predicted:Human,Dog,Cow,Horse,Zebrafish,Sheep) 推薦應用:WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN40323R-200ul

    200ul

    ¥3490.00

    交叉反應:Mouse,Rat(predicted:Human,Dog,Cow,Horse,Zebrafish,Sheep) 推薦應用:WB,IHC-P,IHC-F,ICC,IF,ELISA

產品描述

英文名稱PICALM
中文名稱磷脂酰肌醇結合網格蛋白組裝蛋白抗體
別    名CALM; Clathrin assembly lymphoid myeloid leukemia; Clathrin assembly lymphoid myeloid leukemia protein; CLTH; LAP; Phosphatidylinositol-binding clathrin assembly protein; PICAL_HUMAN; PICALM.  
研究領域神經生物學  信號轉導  Alzheimer's  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Mouse, Rat,  (predicted: Human, Dog, Cow, Horse, Zebrafish, Sheep, )
產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量71kDa
細胞定位細胞漿 細胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human PICALM/CALM:251-350/652 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產品介紹This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10;11)(p13;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

Function:
Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction.

Subunit:
Binds clathrin; involves primarily the C-terminal sequences, but the full-length protein is required for full binding capacity. Binds phosphatidylinositol 4,5- bisphosphate.

Subcellular Location:
Membrane, clathrin-coated pit. Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Colocalized with clathrin in the Golgi area.

Tissue Specificity:
Expressed in all tissues examined.

DISEASE:
Note=A chromosomal aberration involving PICALM is found in diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with MLLT10.

Similarity:
Contains 1 ENTH (epsin N-terminal homology) domain.

SWISS:
Q13492

Gene ID:
8301

Database links:

Entrez Gene: 8301 Human

Entrez Gene: 233489 Mouse

Entrez Gene: 89816 Rat

Omim: 603025 Human

SwissProt: Q13492 Human

SwissProt: Q7M6Y3 Mouse

SwissProt: O55012 Rat

Unigene: 163893 Human

Unigene: 235175 Mouse

Unigene: 24871 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


主站蜘蛛池模板: 国产无套内射普通话对白 | 国产最新精品视频 | 无码精品一区二区三区在线播放 | 国产精品一二区 | 国产午夜精品爆乳美女视频免费 | 91精品国产综合久久久四虎 | 成人做爰黄A片免费看三区爱奴 | 丰满少妇乱子伦精品看片 | 国产福利视频在线 | 麻豆免费视频 | 国产三级午夜理伦三级 | 国产片成人av在线观看 | 精品人妻伦九区久久AAA片 | 午夜国产视频 | 日韩伦理在线 | 人妻无码一区二区三区 | 熟女大屁股 | 波多野结av衣东京热无码专区 | 夜夜夜干| 精品久久久久久久久久久久久久 | 人人操人人摸超碰 | 美国色网站 | 亚洲欧美日韩另类在线 | 日本乱伦视频 | 极品少妇一区二区三区 | 亚洲AV网址| 日屄免费视频 | 自拍偷在线精品自拍偷无码专区 | 国产精品三级久久久久久电影 | 视频在线一区二区 | 精品国自产拍在线观看 | 你懂的国产 | 日乱伦视频 | 亚洲AV高清 | 韩国大尺度原声做爰网站 | 无码性按摩AV在线观看 | av无码电影在线观看 | 在线成人A片免费观看网址 国产美女裸体无遮挡网站 亚洲精品91 | 国产成人三级在线 | 国产精品18| 91玉足脚交白嫩脚丫在线播放 |